Concurrent Training Interference Tax Calculator (AMPK-mTOR & Glycogen Clock)

Powered by the Struggl Concurrent Interference Subsystem and POST /v1/public/tax. Audits weekly hybrid training schedules against 5 deterministic physiological rules derived from Wilson et al. (2012), Robineau et al. (2016), Schumann et al. (2022), and Seiler (2010).

Rule 1 — Same-Day Proximity (< 3.0h HIGH -25 pts; 3.0-5.9h MODERATE -12 pts): Acute endurance AMPK activation phosphorylates TSC2 and inhibits mTORC1 myofibrillar protein synthesis when lower-body lifting follows within 3 hours (Robineau et al. 2016, DOI: 10.1519/JSC.0000000000000798).
Rule 2 — Glycogen Depletion Before Legs (>= 15 km or >= 90 min run within 36h before heavy legs, HIGH -25 pts): Local vastus lateralis glycogen depletion reduces squat/leg-press volume capacity by 15-22%.
Rule 3 — Eccentric Hinge Window (Quality run within 48h after heavy RDL/Squat, MODERATE -12 pts): Sarcomere Z-disk micro-damage elevates running oxygen cost by 3-7% (Fyfe et al. 2014, DOI: 10.1007/s40279-014-0162-1).
Rule 4 — Back-to-Back Quality Runs (<= 24h between threshold/VO2max sessions, MODERATE -12 pts).
Rule 5 — Polarization Drift (> 20% hard endurance sessions across >= 4 weekly runs, LOW -5 pts, Seiler 2010, DOI: 10.1123/ijspp.5.3.276).

Component	Deterministic Specification & Literature Benchmark
Rule / Benchmark 01	Rule 1 — Same-Day Proximity (< 3.0h HIGH -25 pts; 3.0-5.9h MODERATE -12 pts): Acute endurance AMPK activation phosphorylates TSC2 and inhibits mTORC1 myofibrillar protein synthesis when lower-body lifting follows within 3 hours (Robineau et al. 2016, DOI: 10.1519/JSC.0000000000000798).
Rule / Benchmark 02	Rule 2 — Glycogen Depletion Before Legs (>= 15 km or >= 90 min run within 36h before heavy legs, HIGH -25 pts): Local vastus lateralis glycogen depletion reduces squat/leg-press volume capacity by 15-22%.
Rule / Benchmark 03	Rule 3 — Eccentric Hinge Window (Quality run within 48h after heavy RDL/Squat, MODERATE -12 pts): Sarcomere Z-disk micro-damage elevates running oxygen cost by 3-7% (Fyfe et al. 2014, DOI: 10.1007/s40279-014-0162-1).
Rule / Benchmark 04	Rule 4 — Back-to-Back Quality Runs (<= 24h between threshold/VO2max sessions, MODERATE -12 pts).
Rule / Benchmark 05	Rule 5 — Polarization Drift (> 20% hard endurance sessions across >= 4 weekly runs, LOW -5 pts, Seiler 2010, DOI: 10.1123/ijspp.5.3.276).

Verified Scientific DOIs: 10.1519/JSC.0b013e31823a3e2d, 10.1519/JSC.0000000000000798, 10.1007/s40279-021-01587-7, 10.1007/s40279-014-0162-1, 10.1123/ijspp.5.3.276